Pemanfaatan Tawas sebagai Sediaan Antiperspiran dan Pasca-Cukur

  • Ani Haerani Fakultas Farmasi, Institut Kesehatan Rajawali, Bandung
  • Putri Apriliana Fakultas Farmasi, Institut Kesehatan Rajawali, Bandung
  • Cindy Putri Apriliani Fakultas Farmasi, Institut Kesehatan Rajawali, Bandung
  • Euis Nuraeni Fakultas Farmasi, Institut Kesehatan Rajawali, Bandung
  • Anggi Dwi Astuti Fakultas Farmasi, Institut Kesehatan Rajawali, Bandung

Abstract

Body odor in humans usually occurs due to the overproduction of sweat glands and the presence of bacteria. Antiperspirants are cosmetic preparations that are used to restrain the release of excessive amounts of sweat by narrowing the pores of the sweat glands, both eccrine and apocrine. This study aims to make deodorant spray/stick/stick preparations by utilizing natural ingredients, namely alum. In this study, several tests were used including organoleptic tests, irritation tests, pH tests, melting time tests, melting point tests, and antiperspirant tests. Alum powder has wide traditional use as an astringent to prevent bleeding from minor wounds and promote their healing. Therefore, dosage forms are more precisely designed with suitable concentrations (2% gel) to extend their astringent activity with higher retention times due to the highly viscous nature of the gel. Using suitable excipients, 2% lotions and gels were prepared by the dispersion method while emulsifiers were used for the preparation of potassium alum cream of equal strength. The research results obtained were homogeneous, did not cause irritation to the skin, yellowish green in color and showed no change in the formulation which showed its stability as a dosage form and its size as a commercial product line.

References

Dewi, Shinta. 2021. Kajian Pustaka Dalam Penentuan Tipe Dan Permasalahan Kulit Wajah. Jurnal SNATI, Vol. 1(1).

Tarwoto & Wartonah. (2006), Kebutuhan dasar manusia dan proses keperawatan. Edisi 3.Salemba Medika, Jakarta.

Wen, H. W. (2009). Ablation of Apocrine Glands With The Use Of Suction-assisted Cartilage Shaver For Treatment Of Axillary Bromhidrosis. Archive of Dermatological Research, 272, 321-329.

Mutachler, E. 1991. Dinamika Obat. Edisi V 88. Penerbit ITB. Bandung.

Rahmawaty, Dina dan Sari, Destria I. 2019. Buku Ajar Teknologi Kosmetik. CV IRDH. Malang.

Young, A. 1974. Practical Cosmetic Sciense. Mills dan Boon Limited: London.

Wasitaatmadja, S.M. 1997. Penuntun Ilmu Kosmetik Medik. Jakarta: UI-Press.

Egbuobi, R. C., Ojiegbe, G. C., Dike-ndudim, J. N., dan Enwun, P. C. 2013. Antibacterial Activities of different brands of deodorants marketed inowerrri, imo state, Nigeria. African Journal of clinical and experimental microbiologi 14 (1): 14-1.

Fatmawaty, A., Manggau, M. A., Tayeb, R., & Adawiah, R. (2016). Uji Iritasi Krim Hasil Fermentasi Bunga Rosella (Hibiscus sabdariffa L.) dengan Variasi Konsentrasi Emulgator Novemer Pada Kulit Kelinci (Oryctalagus cuniculus). Journal of Pharmaceutical and Medicinal Sciences, 1(2), 62-65.

Irsan, M. A., Manggav, E., Pakki, & Usmar. (2013). Uji Iritasi Krim Antioksidan Ekstrak Biji Lengkeng (Euphoria Longana Stend) Pada Kulit Kelinci (Oryctolagus Cuniculus). Majalah Farmasi dan Farmakologi, 2(17), 55-60.

British pharmacopoeia, volume I&II, 2011.

Goel AK, et al., (1985) Intravesical irrigation with alum for the control of massive bladder hemorrhage. J Urol ; 133: 956-7.[ v.16(4); Oct-Dec 2009]

Kelber CJ and Putt MS, (1984). Alum and dental caries – a review of the literature. Clinprev dent, 6(6); 14-25

Mourghan k, and Suryakan TH M P. (2004); Evaluation of an alum – containing mouth rinse for inhibition of streptococcus mutans level in children, collage of dental surgery, Mangalore, Manipal academy

Sarfaraz K. Niazi,(2004) Handbook of Pharmaceutical Manufacturing Formulations, formulation of semi solids, vol 4

Kuntal Das, Raman Dang, et al. (2012). Evaluation for safety assessment of formulated vanishing cream containing aqueous Stevia extract, Indian Journal of Novel Drug Delivery 4(1), Jan-Mar, 43-51

Alrosyidi, Achmad F. dan Syaifatul. 2021. Formulasi, Evaluasi Mutu Fisik dan Uji SPF Krim Tabir Surya Berbahan Dasar Rumput Laut E. cottonii. Majalah Farmasi dan Farmakologi. 25 (1). 15-19

Syed Nisar, Hussain Shah, et al. (2013). Formulation Study of Topically Applied Lotion: In Vitro and in vivo evalution, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan; BioImpacts, 3(1), 11- 19.* Bioimpacts › v.3(1); 2013

Published
2024-04-19